CAS号:10238-21-8-格列苯脲 - Glyburide-科华智慧

1. 主信息

英文名:	Glyburide
中文名:	格列苯脲
CAS编号:	10238-21-8
化学分子式：	C₂₃H₂₈ClN₃O₅S
化学分子量：	494.0 g/mol
SMILES：	COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
来源：	合成化合物
结构类型：	-
其它名称或标识：	Daonil Diabeta Euglucon 5 Euglucon N Glibenclamide

2. 供应商与价格

供应商	包装规格	含量	价格(元)	环境要求	货期	说明
科华智慧	20mg	HPLC≥98%	400	-20℃	现货	-
科华智慧	5g	98%	40	-20℃	现货	-
科华智慧	25g	98%	96	-20℃	现货	-
科华智慧	100g	98%	376	-20℃	现货	-

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3. 结构

3.1 二维结构

3.2 三维结构

-1 -2 -3 61 63 0 0 0 0 0 0 0999 V2000 3.1470 0.0558 -4.0837 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -4.0776 1.3631 -0.3981 S 0 0 0 0 0 0 0 0 0 0 0 0 -2.4784 -0.9169 -1.7731 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.2743 1.3435 -1.8347 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.1090 1.8834 0.4784 O 0 0 0 0 0 0 0 0 0 0 0 0 1.9730 0.8376 1.9591 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5342 -1.2547 1.6291 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.6516 -2.3243 0.0526 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.6209 -0.1965 0.1324 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4795 2.5797 0.5136 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.9155 -3.4350 -0.5090 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4497 -4.7719 0.0160 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4136 -3.2928 -0.2400 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0895 -5.0103 1.4824 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0567 -3.5336 1.2268 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5891 -4.8746 1.7230 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8734 -1.1463 -0.6339 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6061 2.2808 -0.0567 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3015 3.7187 0.4775 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9398 4.4938 0.7652 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6285 2.3773 -1.0318 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4586 2.8861 1.1794 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4671 3.1019 -0.7626 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2973 3.6104 1.4486 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0617 3.6484 1.3808 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3992 1.2418 0.8804 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8958 0.2599 -0.1178 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4369 -0.9365 0.3074 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7965 0.5865 -1.4558 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8978 -1.8454 -0.6453 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2576 -0.3223 -2.4083 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8080 -1.5383 -2.0031 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7312 -0.8695 2.3015 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0694 -3.4107 -1.5951 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.5388 -4.8198 -0.1030 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0276 -5.5860 -0.5871 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1289 -4.0202 -0.8574 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0600 -2.2989 -0.5401 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4172 -6.0133 1.7791 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6295 -4.3028 2.1227 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4660 -2.7251 1.8447 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0321 -3.5034 1.3480 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0628 -5.6878 1.2081 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3755 -4.9835 2.7922 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9825 -2.3880 1.0102 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9469 -0.4850 1.0634 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3000 4.9599 -0.1617 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7081 5.3277 1.4401 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7369 1.9020 -2.0016 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2174 2.8070 1.9515 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2986 3.1800 -1.5298 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1782 4.0829 2.4201 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7471 3.2489 2.3511 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9397 4.2803 1.5527 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9273 2.8498 -0.3557 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3423 1.5115 -1.7979 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3266 -2.7952 -0.3371 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1707 -2.2564 -2.7342 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8904 0.2111 2.2298 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6328 -1.1387 3.3566 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5906 -1.4029 1.8831 H 0 0 0 0 0 0 0 0 0 0 0 0 1 31 1 0 0 0 0 2 4 2 0 0 0 0 2 5 2 0 0 0 0 2 9 1 0 0 0 0 2 18 1 0 0 0 0 3 17 2 0 0 0 0 6 26 2 0 0 0 0 7 28 1 0 0 0 0 7 33 1 0 0 0 0 8 11 1 0 0 0 0 8 17 1 0 0 0 0 8 45 1 0 0 0 0 9 17 1 0 0 0 0 9 46 1 0 0 0 0 10 25 1 0 0 0 0 10 26 1 0 0 0 0 10 55 1 0 0 0 0 11 12 1 0 0 0 0 11 13 1 0 0 0 0 11 34 1 0 0 0 0 12 14 1 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 13 15 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 14 16 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 15 16 1 0 0 0 0 15 41 1 0 0 0 0 15 42 1 0 0 0 0 16 43 1 0 0 0 0 16 44 1 0 0 0 0 18 21 2 0 0 0 0 18 22 1 0 0 0 0 19 20 1 0 0 0 0 19 23 2 0 0 0 0 19 24 1 0 0 0 0 20 25 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 21 23 1 0 0 0 0 21 49 1 0 0 0 0 22 24 2 0 0 0 0 22 50 1 0 0 0 0 23 51 1 0 0 0 0 24 52 1 0 0 0 0 25 53 1 0 0 0 0 25 54 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 28 30 1 0 0 0 0 29 31 2 0 0 0 0 29 56 1 0 0 0 0 30 32 2 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 32 58 1 0 0 0 0 33 59 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0

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4. 国际命名与标识

4.1 IUPAC Name

5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide

4.2 InChl

InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)

4.3 InChlKey

ZNNLBTZKUZBEKO-UHFFFAOYSA-N

4.4 Canonical SMILES

COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

4.5 lsomeric SMILES

4.6 SDF文件

补充中

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5. 波谱数据

5.1 ¹³C核磁共振谱(¹³C NMR)

5.2 ¹H核磁共振谱(¹H NMR)

5.3 质谱(MS)

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5.4 红外光谱(IR)

补充中

5.5 紫外/可见光谱(UV/Vis)

补充中

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6. 相关药材

中文名称

英文名称

拉丁文名称

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7. 相关靶点

基因靶点

靶点位置

参考文献

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8. 相关疾病

疾病名称

疾病类型